Posterior Lumbar Interbody Fusion
PLIF is generally used to treat back or leg pain caused by degenerative disc disease. The surgeon will stabilize the spine by fusing vertebrae together with bone graft material.
Posterior lumbar interbody fusion (PLIF) is a spinal surgical procedure performed to provide relief from debilitating pain in the lumbar (lower) region of the spine. PLIF is performed by through the patient's back. A posterior approach can be advantageous since it avoids interfering with the many organs and major blood vessels present in the abdominal region. Also, a posterior approach brings the surgeon to the affected site more quickly. Interbody fusion involves removing an interverterbal disc, replacing it with a bone spacer and fusing the two vertebrae on either side.
PLIF is a successful treatment for a number of lower back problems, such as spondylothesis and disc space collapse, also known as disc degeneration, that have not responded to more conservative therapies. Prior to the procedure, detailed images of the spine are produced using MRI and CT scans. In addition to confirming the diagnosis, these images allow the surgeon to pinpoint the exact location of the problem and to determine which implant device is most appropriate for use in the repair.
The PLIF Procedure
The PLIF procedure is performed with the patient under general anesthesia, positioned face down on the operating table. The treatment site is cleansed with an antiseptic and the surgeon makes a three-to six-inch incision in the midline of the back near the affected portion of the spine. Tools are used to separate and retract the muscles. An imaging device will ensure that the precise vertebrae are targeted. Next, the lamina, or outer covering of the spinal cord, is removed and any excess bone is trimmed back to present an unobstructed view of the nerve roots. The injured disc, bone spurs and any debris are then removed. This recreates a space for the nerves that have been compressed, relieving pain and symptoms in the lower back and legs.
To fill the space that has been created, a bone graft or bone morphogenetic proteins are placed in the open disc area and instrumentation is affixed as needed to maintain spinal stability. The hardware used often includes two spacers containing the graft material, with one positioned on each side of the interbody space. The surgeon carefully inserts the spacers, avoiding the spinal cord and adjacent nerves. In addition, metal plates, rods and screws will be attached to the vertebrae to hold the spinal bones in place as they grow together.
Bone morphogenetic protein (BMP) is an FDA-approved treatment used in conjunction with spinal fusion surgery to stimulate bone growth within the treated area and achieve optimal results without the need for a bone graft. Bone grafts taken from another part of the patient's own body or obtained from donor bone, however, are also highly successful. Once the operation is complete, imaging is used once again to confirm the placement of instrumentation. Finally, the incision is closed with sutures or surgical staples. PLIF procedures may vary in length, generally lasting between 3 and 6 hours, depending on the extent of the spinal damage.
Recovery from a PLIF Procedure
After undergoing a PLIF procedure, a patient typically remains in the hospital for 3 to 5 days. A physical therapy regimen is started soon after to assist the patient in regaining strength and mobility. Certain activities are restricted during the recovery period, including heavy lifting, twisting the midsection,and bending at the waist. Many patients can return to work 2 to3 weeks after the procedure. After 3 months, patients can resume more rigorous activities, including some sports. The duration of a full recovery depends on the number of vertebrae that have been fused during surgery and the patient's individual healing process.
Risks of a PLIF Procedure
While PLIF is considered a safe procedure, like any spinal surgery it carries some risks. While uncommon, the most frequent complication is nonunion, which means the bones do not fuse properly. This is more likely to occur in those who smoke, are obese, have previously undergone a spinal surgery or have undergone radiation treatments. There is also the minor risk that the patient's pain will persist after surgery. Other risks of PLIF, or of any surgical procedure, include the possibility of infection, excessive bleeding, blood clot and adverse reaction to anesthesia or medication.